Channel: Professor Dave Explains

Category: Education

Tags: prodrugfolylpolyglutamate synthetasemethotrexate polyglutamatemethotrexatedmardsfolic acidrheumatoid arthritismichael e weinblattdihydrofolate reductase

Description: In the previous tutorial we introduced antirheumatic drugs called DMARDs. Now let's discuss in greater detail a particular small molecule DMARD called methotrexate. This was originally designed to be an anti-cancer drug, but it was fortuitously found to be effective against rheumatoid arthritis, among other inflammatory diseases. How does this drug work? Let's find out! Script by Chris Hofmann Watch the whole Pharmacology playlist: bit.ly/ProfDavePharma General Chemistry Tutorials: bit.ly/ProfDaveGenChem Organic Chemistry Tutorials: bit.ly/ProfDaveOrgChem Biochemistry Tutorials: bit.ly/ProfDaveBiochem Biology/Genetics Tutorials: bit.ly/ProfDaveBio Anatomy & Physiology Tutorials: bit.ly/ProfDaveAnatPhys Biopsychology Tutorials: bit.ly/ProfDaveBiopsych Microbiology/Infectious Diseases Tutorials: bit.ly/ProfDaveMicrobio History of Drugs Videos: bit.ly/ProfDaveHistoryDrugs Immunology Tutorials: bit.ly/ProfDaveImmuno EMAIL► ProfessorDaveExplains@gmail.com PATREON► patreon.com/ProfessorDaveExplains Check out "Is This Wi-Fi Organic?", my book on disarming pseudoscience! Amazon: amzn.to/2HtNpVH Bookshop: bit.ly/39cKADM Barnes and Noble: bit.ly/3pUjmrn Book Depository: bit.ly/3aOVDlT