Channel: Dr. Najeeb Lectures

Category: Education

Tags: cholinergic receptorsreceptorshow receptors worktypes of receptorsagonistusmle step 1usmlealpha receptorsdr najeeb lecturesarmando hasudunganmuscarinic receptorsreceptorreceptors explainedeasy receptorsphysiology receptorsadrenergic receptorsnicotinic receptorsdr najeebthe agonistpharmacodynamics dr najeebsignal transduction pathway

Description: #Receptors #Agonist #DrNajeeb Like this video? Sign up now on our website at DrNajeebLectures.com to access 800+ Exclusive videos on Basic Medical Sciences & Clinical Medicine. These are premium videos (NOT FROM YOUTUBE). All these videos come with English subtitles & download options. Sign up now! Get Lifetime Access for a one-time payment of $99 ONLY! In this video Dr. Najeeb discusses the following points. 00:00:00 - 00:01:50 Brief overview of previous lecture 00:01:50 - 00:03:15 What is an agonist? 00:03:15 - 00:04:56 What is the difference between agonist and antagonist? 00:04:56 - 00:05:22 Different types of agonists 00:05:22 - 00:06:20 Full agonist 00:06:20 - 00:08:24 What is affinity? 00:08:24 - 00:10:30 Efficacy of ligand (intrinsic activity) 00:10:30 - 00:15:13 Partial Agonist 00:15:13 - 00:16:20 Full agonist vs Partial agonist 00:16:20 - 00:20:00 Partial agonists as antagonists 00:20:00 - 00:24:00 Rationale of use of partial agonists as drugs 00:24:00 - 00:28:50 Examples of full agonists, partial agonists, and opioid receptors 00:28:50 - 00:35:54 Orthosteric agonist vs Allosteric agonist 00:35:54 - 00:40:37 Positive Allosteric Modulator 00:40:37 - 00:49:57 Inverse agonist with examples 00:49:57 - 00:51:53 allosteric agonist example 00:51:53 - 00:52:40 Positive Allosteric Modulator example 00:52:40 - 00:59:01 How Benzodiazepines work 00:59:01 - 01:03:38 Benzodiazepines vs Barbiturates 01:03:38 - 01:12:32 Direct agonist and Indirect agonists 01:12:32 - 01:18:29 Review of the lecture