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Oxford launches trials for new oral vaccine against paratyphoid

Duration: 00:49Views: 1.9KLikes: 35Date Created: Mar, 2022

Channel: University of Oxford

Category: Education

Tags: oxford unioxford studentoxford lifetyphoiduniversity#oxforduniversity of marylanduniversity of oxford#oxforduniversityoxfordenteric feversalmonella#oxforduniparatyphoidoral vaccine

Description: Enteric fever once toppled civilisations. However, it is also still a major scourge today. Caused by typhoid (S. Typhi) and paratyphoid (S. Paratyphi) bacteria, enteric fever tops over 14 million cases each year. Most of these cases are reported in Asia and connected with poverty. Better sanitation and access to clean water are crucial to prevent enteric fever but these take time and rely on political will and economic investment. Vaccines can offer a cost-effect way to minimise the disease burden. While there are now effective vaccines for typhoid, there are no licensed vaccines exist for paratyphoid, which accounts for an estimated 3.3 million cases. The University of Oxford has begun a trial to test a new oral paratyphoid vaccine in human volunteers to check safety and immune responses. The vaccine has been developed by the University of Maryland. It is called a ‘challenge’ trial because participants receive a dose of paratyphoid bacteria to see how well the vaccine works. Participants will be monitored closely and treated if they become unwell. Search 'paratyphoid' to find out more. - - - Oxford is a truly international university, bringing together the best and brightest minds from around the world. Our 13,000 staff and 22,000 students come from a wide range of backgrounds and over 140 countries and territories, making Oxford a diverse and dynamic place to work and study. We believe our strengths lie in empowering our academics and students to address fundamental questions of global significance, while providing all members of the University with a welcoming and inclusive environment that enables individuals to achieve their best work. Find out more: ox.ac.uk Latest news and events: ox.ac.uk/news-and-events Apply to study at Oxford: ox.ac.uk/admissions/undergraduate Apply for graduate study at Oxford: ox.ac.uk/admissions/graduate Applying for continuing education courses at Oxford: ox.ac.uk/admissions/continuing-education Follow Oxford University Twitter: twitter.com/UniofOxford Facebook: facebook.com/the.university.of.oxford Instagram: instagram.com/oxford_uni LinkedIn: linkedin.com/school/oxforduni Medium: medium.com/oxford-university Weibo: e.weibo.com/OxfordUni

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