Channel: Dr. Najeeb Lectures

Category: Education

Tags: endogenous insulininsulinc peptidec peptide testc peptide levelsdiabetes mellitususmle step 1ninja nerddr najeeb lecturesclinical medicinewhat is insulin resistanceneetdr beenninja nerd lectureswhat is insulin deficiencydr najeebinsulin resistancemedecinetype 1 diabetesinsulin deficiencywhat is c peptidemedical lecturesmedicinearmando hasudungantype 2 diabetesexogenous insulinlaboratorydiabetes

Description: #Diabetes #BloodGlucoseRegulation #Insulin Like this video? Sign up now at DrNajeebLectures.com to access 800+ Exclusive videos on Basic Medical Sciences & Clinical Medicine. These are premium videos (NOT FROM YOUTUBE). We upload New Premium videos in members area every week with download option. S Get Lifetime Access to all premium videos for a one-time payment of $99 ONLY! This clip is taken from Q&A session of our 1st live webinar on introduction to diabetes mellitus. In this clip an attendee asked how to differentiate between insulin resistance and insulin deficiency in patients with diabetes mellitus. Insulin deficiency occurs when insulin-producing cells of the pancreas are damaged or destroyed due to which insulin production is stopped or reduced significantly. This can occur in both type 1 and type 2 diabetes mellitus. Insulin resistance is a feature of type 2 diabetes mellitus and involves a reduced response to insulin by insulin-sensitive tissues and cells. There are a number of mechanisms leading to insulin resistance all of which are not yet understood. In short, the answer to this question is by measuring the C-peptide levels in the blood which are increased in insulin resistance and are decreased in insulin deficiency. C-peptide is co-secreted with insulin in equimolar amounts and hence can identify endogenous insulin release.