Channel: Speed Pharmacology

Category: Education

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Description: Coronaviruses are a group of genetically related viruses that cause disease in mammals and birds. In humans, coronaviruses can cause severe acute respiratory syndrome (SARS). In 2019, a new coronavirus was identified as the cause of a disease outbreak in China. The virus was named as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). This pharmacology lecture discusses the stucture and replication cycle of the coronavirus as well as emerging targets for pharmacological antiviral interventions. Drugs mentioned include; Camostat Mesylate, Hesperidin, Remdesivir, Favipiravir, Chloroquine, Lopinavir/Ritonavir, Darunavir/Cobicistat. References/source of selected illustrations: doi.org/10.1016/j.apsb.2020.02.008 doi.org/10.3389/fmicb.2014.00296 doi.org/10.3390/v4040557 doi.org/10.1038/emm.2015.76 Thanks for watching and don't forget to SUBSCRIBE, hit the LIKE button👍 and click the BELL button🔔 for future notifications!!! Like what we do? Learn how to support us on Patreon! 💪patreon.com/speedpharmacology 0:00 Intro 0:45 Structure 1:00 Cell entry 1:26 Entry inhibitors 3:28 Replication 4:23 Replication inhibitors 5:18 Chloroquine 5:47 Other drugs of interest