Channel: iBiology

Category: Science & Technology

Description: iBiology.org Intestinal villi are finger-like projections that line the small intestine, increasing surface area to help with absorption of nutrients. Injuries to the intestinal villi can cause a range of health problems, and can even be life-threatening. In this Share Your Research Talk, physician-scientist trainee Takahiro Ohara discusses his research on the molecular and cellular processes that drive recovery of intestinal villi. He describes the fetal-like state that cells on damaged villi take on, and how adaptive differentiation of these cells leads to proper villus recovery. 0:00 Introduction 2:08 Normal Villus Recovery 4:21 Modeling Villus Injury and Repair 5:10 What happens to enterocytes? 11:10 What drives the fetal program? 15:06 What are the consequences of having abnormal aVECs? 18:00 Summary Speaker Biography: Takahiro Ohara is an MD-PhD student at Washington University in St. Louis. Interested in regenerative medicine, his research focuses on how intestinal villi recover from injury. He received a B.S. from UCLA in Molecular, Cell, and Developmental Biology with a Minor in Biomedical Research. Kevin McLean (iBiology): Producer Brittany Anderton (iBiology): Producer Eric Kornblum (iBiology): Videographer Jiefei Yuan (iBiology): Editor Chris George (iBiology): Graphics Maggie Hubbard (iBiology): Graphics Except where otherwise noted, this work is licensed under creative commons.org/licenses/by-nc-nd/4.0 © 2007-2021 Science Communication Lab™. All rights reserved.