Channel: Reactions

Category: Science & Technology

Tags: chemistryopioid crisisamerican chemical societyeducationheroindrugsaddictionacs reactionsmedicationscience communicationoxycontinmorphineacsopiumoxyscienceoxycodonereactionsopioids

Description: Will we ever have painkillers as good as opioids, but without the risk of addiction and overdose? #opioids #heroin #opioidcrisis You might also like: What Happens When You Overdose?: youtu.be/xLSz3wEgwJ8 Why Are Synthetic Drugs So Dangerous?: youtube.com/watch?v=83gIiBD365E The Top 5 Strangest Poisons That Can Kill You: youtu.be/4hQ0G0GaYR8 Can You Take Expired Drugs?: youtu.be/aT4qzgEQr-Y What is Addiction?: youtu.be/C6I3CHhBGeQ Credits: Executive Producers: George Zaidan Hilary Hudson Producers: Andrew Sobey Elaine Seward Writer/Host: Sam Jones, PhD Scientific consultants: Michelle Boucher, PhD Kelly Dunn, PhD Leila Duman, PhD Kim Janda, PhD Sources: Frederich Serturner pubmed.ncbi.nlm.nih.gov/1786314 Opioid toxicity ncbi.nlm.nih.gov/books/NBK431077 Opioid overdoses--world stats who.int/news-room/fact-sheets/detail/opioid-overdose#:~:text=difficulties%20with%20breathing.-,Worldwide%2C%20about%200.5%20million%20deaths%20are%20attributable%20to%20drug%20use,of%20opioid%20overdose%20in%202017 Opioid death rates in the US drugabuse.gov/drug-topics/trends-statistics/overdose-death-rates#:~:text=Opioid%2Dinvolved%20overdose%20deaths%20rose,in%202018%20with%2046%2C802%20deaths. Inside the Story of America’s 19th-Century Opiate Addiction smithsonianmag.com/history/inside-story-americas-19th-century-opiate-addiction-180967673 Abuse-deterrent opioids pubs.acs.org/doi/10.1021/cen-09545-cover2 NIH solicits research into vaccines that protect against opioid use genengnews.com/insights/nih-solicits-research-into-vaccines-to-protect-against-opioid-use Vaccines against addictive drugs push forward despite past failures cen.acs.org/articles/96/i8/Vaccines-against-addictive-drugs-push.html?utm_source=ACSMembership&utm_medium=Webinar&utm_campaign=CEN Looking beyond opioids for safer pain relief cen.acs.org/articles/95/i45/chemists-responding-opioid-epidemic.html?utm_source=ACSMembership&utm_medium=Webinar&utm_campaign=CEN Opioid abuse timeline (FDA) fda.gov/drugs/information-drug-class/timeline-selected-fda-activities-and-significant-events-addressing-opioid-misuse-and-abuse Overdose death rates drugabuse.gov/drug-topics/trends-statistics/overdose-death-rates#:~:text=Opioid%2Dinvolved%20overdose%20deaths%20rose,in%202018%20with%2046%2C802%20deaths. Prostaglandins chem.libretexts.org/Bookshelves/Biological_Chemistry/Supplemental_Modules_(Biological_Chemistry)/Lipids/Fatty_Acids/Prostaglandins#:~:text=Prostaglandin%20Structure-,Prostaglandins%20are%20unsaturated%20carboxylic%20acids%2C%20consisting%20of%20of%20a%2020,two%2C%20or%20three%20double%20bonds.&text=A%20typical%20structure%20is%20on%20the%20left%20graphic. God’s Own Medicine skepticalinquirer.org/2017/03/gods-own-medicine Heroin pubchem.ncbi.nlm.nih.gov/compound/Heroin Ibuprofen pubchem.ncbi.nlm.nih.gov/compound/Ibuprofen Oxycodone pubchem.ncbi.nlm.nih.gov/compound/Oxycodone Heroin chapter sciencedirect.com/science/article/pii/B0123693977004568 Structure of ibuprofen bound to COX-2 ncbi.nlm.nih.gov/pmc/articles/PMC4276492 Use of Oxycodone in Pain Management ncbi.nlm.nih.gov/pmc/articles/PMC4018705/#:~:text=Oxycodone%20is%20an%20analgesic%20opioid,market%20in%201996%20(2). Overcoming opioids: The quest for less addictive drugs statnews.com/2017/04/17/opioids-quest-less-addictive-drugs Rats prefer sugar to heroin pubmed.ncbi.nlm.nih.gov/28645064 NIDA heroin info drugabuse.gov/sites/default/files/heroinrrs_11_14.pdf Heroin History hazelden.org/HAZ_MEDIA/7988_heroin.pdf Frontline PBS: Opium throughout history pbs.org/wgbh/pages/frontline/shows/heroin/etc/history.html The Ongoing Opioid Prescription Epidemic: Historical Context ncbi.nlm.nih.gov/pmc/articles/PMC4940677 Heroin’s Addiction’s Fraught History theatlantic.com/health/archive/2014/02/heroin-addictions-fraught-history/284001 Heroin Prescription and History core.ac.uk/reader/189542775?utm_source=linkout Addiction medications americanaddictioncenters.org/addiction-medications Opiate history michaelshouse.com/opiate-rehab/history-of-opiates Death Tolls cdc.gov/drugoverdose/epidemic/index.html Overdose Increases cdc.gov/media/releases/2020/p1218-overdose-deaths-covid-19.html Etanercept ncbi.nlm.nih.gov/books/NBK545252 Produced by the American Chemical Society. Join the American Chemical Society! bit.ly/Join_acsmembership